Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement …

MA Pfeffer, E Braunwald, LA Moyé… - New England journal …, 1992 - Mass Medical Soc
… inhibitor captopril attenuated ventricular dilatation and remodeling. We investigated whether
captopril could reduce morbidity and mortality in patients with left ventricular dysfunction …

Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction

MA Pfeffer, GA Lamas, DE Vaughan… - … England Journal of …, 1988 - Mass Medical Soc
… that captopril attenuates ventricular enlargement in a high-risk group provide a rationale
for further evaluation of this therapy in asymptomatic patients with left ventricular dysfunction …

Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators.

JD Rutherford, MA Pfeffer, LA Moye, BR Davis… - Circulation, 1994 - Am Heart Assoc
… of left ventricular ejection fraction suggests that captopril could … with more preserved left
ventricular function. The need for … term captopril therapy, suggesting either an anti-ischemic effect

Captopril reduces left ventricular enlargement induced by chronic volume overload

RG Gay - American Journal of Physiology-Heart and …, 1990 - journals.physiology.org
effects of captopril in the current study with those observed in the rat myocardial infarction
model. In rats with large extensive myocardial infarction, captopril … The effect of captopril was …

… two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information from the Survival and Ventricular Enlargement (SAVE) …

MSJ Sutton, MA Pfeffer, L Moye, T Plappert… - Circulation, 1997 - Am Heart Assoc
… The effect of captopril on LV enlargement in patients at 1 year has been demonstrated in …
effect of captopril on the number of patients who developed LV dilatation and on LV dilatation

Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction

SD Solomon, H Skali, NS Anavekar, M Bourgoun… - Circulation, 2005 - Am Heart Assoc
… The dose of captopril used in VALIANT was the same … ventricular enlargement in follow-up.
In VALIANT, we cannot directly assess the effect of the ARB relative to placebo on ventricular

Effects of early captopril administration on infarct expansion, left ventricular remodeling and exercise capacity after acute myocardial infarction

KG Oldroyd, MP Pye, SG Ray, J Christie, I Ford… - The American journal of …, 1991 - Elsevier
… treatment effects were seen in LV volumes or maximal exercise performance. This study
suggests that early treatment with captopril after AMI can attenuate infarct expansion and …

Effects of early use of captopril on haemodynamics and short-term ventricular remodelling in acute anterior myocardial infarction

J Galcera-Tomas, JAN De La Rosa… - European heart …, 1993 - academic.oup.com
… filling pressures and whether early treatment with captopril alters this process we studied 68
ventricular enlargement is related to the degree of ventricular dysfunction and that captopril

Double-blind comparison of perindopril and captopril in hypertension: effects on left ventricular morphology and function

AM Grandi, A Venco, F Barzizza… - American journal of …, 1991 - academic.oup.com
… To date few data are available concerning its effects on the left ventricle.'6 Therefore, we
planned this study in order to compare the effects of perindopril and captopril on LV morphology …

… of left ventricular hypertrophy with captopril restores normal ventricular action potential duration, dispersion of refractoriness, and vulnerability to inducible ventricular …

SJ Rials, Y Wu, X Xu, RA Filart, RA Marinchak… - Circulation, 1997 - Am Heart Assoc
… with captopril produces regression of hypertrophy, normalizes APD, normalizes dispersion
of refractoriness, and decreases vulnerability to inducible VF in an animal model of LVH. This …