[HTML][HTML] SARS-coV-2 treatment approaches: numerous options, no certainty for a versatile virus

S Iacob, DG Iacob - Frontiers in Pharmacology, 2020 - frontiersin.org
SARS-CoV-… SARS-CoV-2 and other corona viruses or the host-virus interactions and their
similarities with immune system disorders. Still, the pathogenic mechanisms behind SARS-CoV

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

AA Amarilla, JDJ Sng, R Parry, JM Deerain… - Nature …, 2021 - nature.com
… and versatile CPER-based reverse genetic platform for a range of positive-strand RNA viruses
with … , particularly its application for viruses with large genomes like SARS-CoV-2. As new …

A versatile reporter system to monitor virus-infected cells and its application to dengue virus and SARS-CoV-2

F Pahmeier, CJ Neufeldt, B Cerikan, V Prasad… - Journal of …, 2021 - Am Soc Microbiol
… be used to visualize and identify cells infected with dengue virus or SARS-CoV-2. This system
is based on viral protease activity that mediates cleavage and nuclear translocation of an …

Versatile SARS-CoV-2 reverse-genetics systems for the study of antiviral resistance and replication

U Fahnøe, LV Pham, C Fernandez-Antunez, R Costa… - Viruses, 2022 - mdpi.com
… In conclusion, we have developed a highly versatile and robust reverse genetics system
for SARS-CoV-2. This led to the establishment of reporter viruses and subgenomic non-…

Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2

Y Xiang, S Nambulli, Z Xiao, H Liu, Z Sang, WP Duprex… - Science, 2020 - science.org
… The development of highly potent anti–SARS-CoV-2 Nbs may provide a means for versatile,
… We demonstrated the simplicity and versatility of Nb bioengineering and the desirable …

Molnupiravir: A versatile prodrug against SARS-CoV-2 variants

D Teli, P Balar, K Patel, A Sharma, V Chavda, L Vora - Metabolites, 2023 - mdpi.com
… , was found to exert potent anti-SARS CoV-2 activity in in vitro … activity against the omicron
variant of SARS-CoV-2, which is … for the replication of viruses such as SARS-CoV-2 [52]. N4-…

Label-free spectroscopic SARS-CoV-2 detection on versatile nanoimprinted substrates

D Paria, KS Kwok, P Raj, P Zheng, DH Gracias… - Nano …, 2022 - ACS Publications
… and rapid detection of SARS-CoV-2 by exploiting SERS … Raman signal from the SARS-CoV-2
virus, we develop novel … strong signatures of the viral fusion protein of SARS-CoV-2 and …

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

T Thi Nhu Thao, F Labroussaa, N Ebert, P V'kovski… - Nature, 2020 - nature.com
… of the SARS-CoV-2 reverse-genetics system and we expect that this fast, robust and versatile
… of a number of emerging RNA viruses. Although homologous recombination in yeast has …

[PDF][PDF] Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

TTN Thao, F Labroussaa, N Ebert, P V'kovski… - Nature, 2020 - bms.kr
… Our results demonstrate the full functionality of the SARS-CoV-2 reverse-genetics system
and we expect that this fast, robust and versatile synthetic genomics platform will provide new …

ViralFlow: a versatile automated workflow for SARS-CoV-2 genome assembly, lineage assignment, mutations and intrahost variant detection

FZ Dezordi, AMS Neto, TL Campos, PMC Jeronimo… - Viruses, 2022 - mdpi.com
… -scale SARS-CoV-2 Illumina amplicon sequencing data. This workflow automates all steps of
SARS-CoV-2 … by ViralFlow highlight it as a versatile tool for SARS-CoV-2 genomic analysis. …