SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… unique cytokine responses caused by these viruses. Our curation indicates that the cytokine
response induced by SARS-CoV-… viruses, as SARS-CoV-2 does not always induce specific …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… , SARS-CoV-2 and the mechanisms by which cytokine storm is induced by the virus will be
… the context of the rapidly changing cytokine environment after virus infection, we do not have …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
… Antiretrovirals used against the human immunodeficiency virus (HIV), such as lopinavir/ritonavir,
have also been found to reduce the viral load of SARS-CoV-2 [26]. Chloroquine has …

SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses

M Kohyama, T Suzuki, W Nakai, C Ono… - International …, 2023 - academic.oup.com
… decreased in ORF8-knockout SARS-CoV-2-infected hamsters… Similar pro-inflammatory
cytokine production was observed … ORF8 protein is a SARS-CoV-2 viral cytokine involved in the …

Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections

T Okabayashi, H Kariwa, S Yokota, S Iki… - Journal of medical …, 2006 - Wiley Online Library
SARSCoV on IFN system and proinflammatory cytokine production to clarify the pathogenesis
of this virus … defense against virus infection requires IFN-b production in virus infected cells…

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

X Chen, B Zhao, Y Qu, Y Chen, J Xiong, Y Feng, D Men… - MedRxiv, 2020 - medrxiv.org
… of cytokines such as IL-6. We have to point out that due to the shortage of detection kit, the
results of other cytokines … Our research indicated that serum SARS-CoV-2 viral load and IL-6

SARS-CoV-2 and viral sepsis: observations and hypotheses

H Li, L Liu, D Zhang, J Xu, H Dai, N Tang, X Su, B Cao - The Lancet, 2020 - thelancet.com
coronavirus 2 (SARS-CoV-2) and SARS-CoV, we have put forward several hypotheses about
SARS-CoV-… primary source of the cytokine storm in response to SARS-CoV-2 infection and …

Immune response to SARSCoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
SARS-CoV-2 spike protein harbors a polybasic furin cleavage … distinct from SARS-CoV and
other SARS-like viruses. Indicated … the Ebola virus Tim-1 protein can induce a cytokine storm. …

Cytokine profiling in different SARS-CoV-2 genetic variants

ZR Korobova, NA Arsentieva, NE Liubimova… - International Journal of …, 2022 - mdpi.com
… that are associated with different SARS-CoV-2 genetic variants. … virus and the host immune
system by assessing concentrations of cytokines in patients infected with different SARS-CoV-…

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARSCoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… The two central pro-inflammatory cytokines generated during viral infections are IL-6 and
IL-1, which cause hepatocytes to secrete acute-phase proteins, activating the complement …