[HTML][HTML] … pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine storm and inflammatory responses

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
… Careful scrutiny on the characteristics of the viral particles, … , including the role of cytokine
storm in generating acute … discussed to control the cytokine storm or hypercytokinemia. …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… we focus on the cytokine storm in the context of virus infection, … importance of the kinetics of
cytokine gene expression and the … in dissemination of the 1918 virus to brain and spleen (27). …

[HTML][HTML] The potential role of cytokine storm pathway in the clinical course of viral respiratory pandemic

G Murdaca, F Paladin, A Tonacci, S Isola, A Allegra… - Biomedicines, 2021 - mdpi.com
cytokine storm during the infection of these pandemic viruses, … in the election of medical
treatments for these viral diseases. … shows how the cytokine storm may favor viral dissemination. …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and
failure of host protective immunity that results in unrestrained viral dissemination and organ …

[HTML][HTML] Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
… therapeutic options to ameliorate cytokine storm pathology during respiratory viral infection.
… inflammatory responses, hemorrhage and disseminated intravascular coagulation in the …

[HTML][HTML] Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… Severe manifestations of COVID-19 are caused by a combination of direct tissue injury
by viral replication and associated cytokine storm resulting in progressive organ damage. …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
viruses can interfere with the chemokine/chemokine-receptors system using their own
properties to modify intracellular signaling with the final result to further disseminate the infection. …

[HTML][HTML] Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… Downstream production of interferons promotes intracellular antiviral defenses in neighboring
epithelial cells which may limit viral dissemination, while the release of IL-6 and IL-1β from …

Zika virus in the eye of the cytokine storm

C Maucourant, GAN Queiroz, A Samri… - European Cytokine …, 2019 - Springer
… As previously described for other flaviviruses, viral dissemination occurs via the skin, at the
site of the mosquito bite, into the extracellular space of the dermis [19]. The initial step in the …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… that can cause cytokine storms is influenza A virus, in … cells and cytokines in the lungs than
seasonal influenza viruses. This … bacterial replication and dissemination uncontrolled by the …