[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… -19, suggesting that COVID-19 mortality might be due to virus-activated cytokine storm 26 .
… performed, with close monitoring of disseminated intravascular coagulation markers 116 , …

Are superantigens the cause of cytokine storm and viral sepsis in severe COVID‐19? observations and hypothesis

V Scaglioni, ER Soriano - Scandinavian Journal of Immunology, 2020 - Wiley Online Library
… produce disseminatedcytokines by monocytes and dysregulation of lymphocytes
characterized by CD4 lymphopenia and subsequently B cell lymphopenia, 20 but the presence viral

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… The two central pro-inflammatory cytokines generated during viral infections are IL-6 and
IL-… to moderate, hypercoagulation and disseminated intravascular coagulation have all been …

Modelling of cytokine storm in respiratory viral infections

C Leon, AA Tokarev, VA Volpert - Computer Research and Modeling, 2022 - hal.science
viral load. In order to study the emergence and dynamics of cytokine storm, we consider
proinflammatory cytokines … in the normal inflammatory state specific for viral infections or, due to …

[PDF][PDF] An update on cytokine storm in covid-19 infection: Pivotal to the survival of the patients

EI Obeagu, S Hamisi, UO Bunu - Int. J. Adv. Res. Biol. Sci, 2023 - researchgate.net
Cytokine storms can be caused by a number of infectious and noninfectious etiologies,
especially viral respiratory … In thecase of disseminated infections, increased levels of circulating …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… by macrophage activation syndrome and cytokine storm. Various genetic mutations … of
cytokine storm in COVID-19. Once, immunologic complications like cytokine storm occur, anti-viral

[PDF][PDF] Cytokine release and endothelial dysfunction: a perfect storm in orbivirus pathogenesis

EW Howerth - Vet Ital, 2015 - academia.edu
… Dendritic cells then carry the virus to the regional lymph node where replication occurs and
may trigger a cytokine storm. Virus is disseminated from the regional lymph node to many …

Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major players …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
… endotheliitis with apoptotic bodies and viral inclusion in various organs. Severe inflammation
with endotheliitis may lead to disseminated intravascular coagulation with subsequent …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… restricting the dissemination of H5N1 viruses. TNF-α is a key cytokine in cytokine storm and
… in survival when compared with controls following a challenge with the H5N1 virus. IL-1 and …

Influenza infection, SARS, MERS and COVID-19: cytokine storm–the common denominator and the lessons to be learned

VA Ryabkova, LP Churilov, Y Shoenfeld - Clinical Immunology, 2021 - Elsevier
virus infections pose a continuing threat to human life. Cytokine storm syndromes of viral
origin … is closely related to coagulopathy and disseminated intravascular coagulation [36,37]. …