The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… and critical to combat viral infections by promoting viral clearance and regulating innate and
… still unknown when the infection occurs, the RNA of SARS-CoV-2 virus may be recognized …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… of viral-induced cytokine storm and was confirmed to have improved the outcome in infections,
such … of cytokine amplification during influenza virus infection. Cell 2011; 146: 980–991. …

Targeting inflammation and cytokine storm in COVID-19

Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… While an adequate release of cytokines is critical for the body's defense against viral infection,
… When suffering from virus infection, BRD4 plays a role in epithelial-driven and NF-κB …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… like cytokine storm occur, anti-viral treatment alone is … viral infection but goes out of control
after a while and progresses towards a deadly result with development of the cytokine storm

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
viral diseases such as SARS, MERS and influenza, where the development of a cytokine storm
… In viral infections, the aberrant release of pro-inflammatory factors leads to lung epithelial …

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

F Coperchini, L Chiovato, L Croce, F Magri… - Cytokine & growth factor …, 2020 - Elsevier
… diseases, and since 2005, it was associated to the avian H5N1 influenza virus infection [9].
Apart from the immediate significance of the term cytokine storm, the biological and clinical …

The potential role of cytokine storm pathway in the clinical course of viral respiratory pandemic

G Murdaca, F Paladin, A Tonacci, S Isola, A Allegra… - Biomedicines, 2021 - mdpi.com
… Particularly in respiratory virus infections, the cytokine storm plays a primary role in the
pathogenesis of respiratory disease and the clinical outcome of respiratory diseases, leading to …

New fronts emerge in the influenza cytokine storm

XJ Guo, PG Thomas - Seminars in immunopathology, 2017 - Springer
… , including IL-33 and amphiregulin, whose functions are relatively recently appreciated in
influenza virus infection. In this review, we focus on the secretion, regulation, and functions of …

T cell immunobiology and cytokine storm of COVID‐19

XH Luo, Y Zhu, J Mao, RC Du - Scandinavian journal of …, 2021 - Wiley Online Library
… and non-infectious diseases. The first use of ‘cytokine storm’ appears to be on graft-versus-host
disease published in 1993 42 and later in virus infectious diseases including …

Interferon lambdas: the next cytokine storm

C Kelly, P Klenerman, E Barnes - Gut, 2011 - gut.bmj.com
… Plasmacytoid monocyte-derived dendritic cells (pDC and MDDC) and macrophages produce
IFNλ in response to influenza virus infection and/or to bacterial and viral molecular mimics (…