SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has … SARS-CoV-2 develop a mild
to moderate disease with virusvirus particles may facilitate spreading of SARS-CoV-2 in the …

Virology, transmission, and pathogenesis of SARS-CoV-2

M Cevik, K Kuppalli, J Kindrachuk, M Peiris - bmj, 2020 - bmj.com
viral response phase and an inflammatory second phase. Most clinical … SARS-CoV-2
pathophysiology, including virology, transmission dynamics, and the immune response to the virus. …

Understanding the role of SARS-CoV-2 ORF3a in viral pathogenesis and COVID-19

J Zhang, A Ejikemeuwa, V Gerzanich, M Nasr… - Frontiers in …, 2022 - frontiersin.org
… of SARS-CoV-2 ORF3a, and its role in viral pathogenesis and … viral protein that is specific
to SARS-CoV/SARS-CoV-2. It was … β-CoV lineage and likely originated from bats through viral

SARS-CoV-2 accessory proteins in viral pathogenesis: knowns and unknowns

N Redondo, S Zaldívar-López, JJ Garrido… - Frontiers in …, 2021 - frontiersin.org
viral SARS-CoV-2 pathogenesis in COVID-19. Accessory proteins in SARS-CoV-2 consist of
eleven viral … Here, a review on the current knowledge of SARS-CoV-2 accessory proteins is …

The four horsemen of a viral Apocalypse: The pathogenesis of SARS-CoV-2 infection (COVID-19)

P Domingo, I Mur, V Pomar, H Corominas… - …, 2020 - thelancet.com
… Severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 lights the wick by infecting
… The viral feedback loop includes evading the host's innate response, uncontrolled viral

Viral pathogenesis of SARS-CoV-2 infection and male reproductive health

S Roychoudhury, A Das, NK Jha, KK Kesari… - Open …, 2021 - royalsocietypublishing.org
… of SARS-CoV-2. It may cause severe complications in infected couples. This review focuses
on the pathophysiology of potential SARS-CoV-2 … in vulnerability to SARS-CoV-2 infection …

SARS-CoV-2 and ORF3a: nonsynonymous mutations, functional domains, and viral pathogenesis

E Issa, G Merhi, B Panossian, T Salloum, S Tokajian - Msystems, 2020 - Am Soc Microbiol
SARS-CoV-2 of functional domains in the 3a protein linked to virulence, infectivity, ion
channel formation, and virus … the localization and tree topology of the 3a protein in SARS-CoV-2. …

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

T Kehrer, A Cupic, C Ye, S Yildiz, M Bouhaddou… - Cell Host & Microbe, 2023 - cell.com
… syndrome coronavirus 2 (SARS-CoV-2) … viruses carrying a deletion or loss-of-function (LoF)
mutation in ORF6. ORF6 plays key roles in interferon antagonism and viral pathogenesis by …

Mechanisms of SARS-CoV-2 transmission and pathogenesis

AG Harrison, T Lin, P Wang - Trends in immunology, 2020 - cell.com
… its transmissibility and pathogenesis. In this review, we summarize current SARS-CoV-2
research, with an emphasis on transmission, tissue tropism, viral pathogenesis, and immune …

The role of severe acute respiratory syndrome (SARS)-coronavirus accessory proteins in virus pathogenesis

R McBride, BC Fielding - Viruses, 2012 - mdpi.com
… The etiological agent was eventually identified as the SARS human coronavirus (SARS-CoV)
[12]. The virus has been identified as an enveloped, positive-sense RNA virus containing a …