… virus from the rhabdovirus family, vesicular stomatitis virus, and a positive-sense RNA virus,
Zika virus… MGA to identify anti-EBOV compounds and identifies the benzoquinoline series as …

… The relative efficacy of a compound in specifically inhibiting viral replication (as opposed to
inducing cytopathic side effects) was defined as the selectivity index (SI; calculated as CC 50 …

… a large library of well-characterized, known biologically active compounds using automated
… inhibiting HCV replication in this primary screen, we then validated our hit compounds using …

… a compound that inhibits vRNA transcription/replication by … from virus-like RNA as a readout
and virus replication in vitro. … the five compounds on in vitro replication of two influenza virus …

… our assay to efficiently screen around 28,000 compounds against RVFV infection and several
promising inhibitory compounds were identified. The primary screening identified 641 hits (…

… over 140 compounds that suppressed VACV replication. … VACV replication, validating the
effectiveness of our screening. … unknown roles in the VACV replication cycle. Among those in …

… compounds include viral proteins, such as protease or polymerase, and host cell functions
essential for virus replication, … High-throughput screening (HTS) of libraries of small molecules …

… the barrier for efficient culture of SARS-CoV-2 in human cells could benefit basic
investigations in this research field and facilitate the preclinical screening of antiviral compounds. …

… In this study, we screened a set of compounds extracted from Brazilian plants and we identified
four compounds with potent inhibitory activity on HCV replication. These compounds are …

… It was of interest to investigate the effect of the time of compound addition on viral RNA
replication. For … The use of PIPs as a tool for screening compounds for the inhibition of genome …