… The present study was designed to characterize transduction of non-human primate brain
and spinal cord with AAV5 viral vector after parenchymal delivery. AAV5-CAG-GFP (1 × 10 13 …

… Viral vectors that are able to convey robust gene transfer must be combined with efficient brain
… Efficient transduction of non-human primate motor neurons after intramuscular delivery of …

… serotype 2 (AAV2) is transported anterogradely in rat and non-human primate (NHP) brain.
… Altogether, AAV6 raises as an adequate viral vector for neurological diseases. Although its …

… Comparisons of AAV serotype transduction following primate cortical injections have … ,
injections of different AAV serotypes into the primate brain resulted in the following patterns of …

… AAVs efficiently cross the blood–brain barrier in non-human primates. Here we report on …
brains of multiple non-human primate species: marmoset, rhesus macaque and green monkey. …

… Thus, intracerebral injection of viral vector encoding ARSA could be a valuable strategy
to very … that the intracerebral injection of serotype 5 AAV (AAV2-5) in the brain of non-human …

… Incentivized by these desirable properties, we have used CED in recent years to deliver
optogenetic viral vectors into the brains of non-human primates for neuroscientific experiments [8…

… of the blood–brain barrier. Although the use of viral vectors has allowed sustained
expression in neurons, vector administration into the CNS requires neurosurgery to deliver the …

… Schematic representation of the non-human primate brain in coronal section and sites of …
NHP brain parenchyma, as long as one knows the relative affinity of the viral vector serotype …

… by reduced AAV vector transduction in the rat brain following intracranial … Monkey 109 received
an ~10-fold higher dose of viral … towards all serotypes tested compared with monkey 110. …