… -nCoV main protease inhibitor can be extremely fruitful considering its vital role in the viral
life-cycle. The objective of the study is to identify inhibitors from the natural sources that can …

… In the present study, five novel naturally originating hits were discovered by multistep
virtual screening as promising AChE inhibitors. Two of them (9 and 22) are quinolizidine-type …

… as METTL3 inhibitors. … out to virtually screen a library of 1,042 natural compounds based
on the METTL3 crystal structure. On the basis of the virtual screening scores and commercially …

… including available drugs and natural products. Accordingly, this work reports the results of
a virtual screening process aimed at identifying antiviral natural product inhibitors of the SARS…

… model with LIGANDSCOUT for the discovery of new scaffolds acting as HIV-1 non-nucleoside
reverse transcriptase inhibitors by virtual screening of large chemical databases. Six …

… for further screening operations with the aim of finding new lead structures, preferably natural
products, capable of inhibiting the HRV. For the virtual screening filtering experiments, we …

… Using an SBVS approach, this research aimed to find the most powerful inhibitors of
plasmepsine II. The PyRx Virtual Screening Tool was utilized to perform molecular docking of 58 …

… inhibitor of CTSL-meditated substrate cleavage with IC 50 of 2.5 nmol/l. Based on the molecule
fingerprint searching method, 11 natural … compound for CTSL inhibition for SARS therapy. …

… (AChE) inhibitors from natural sources we … 000 natural products. In our study, scopoletin
(1) and its glucoside scopolin (2) emerged as potential AChE inhibitors by the virtual screening …

… a virtual screen with a library of 527 209 natural compounds against the receptor binding
domain of this protein. Top hits from this screen … These findings validate the virtual screening …