… VLA-4. The ot chain cytoplasmic domain is also required for agonist-stimulated adhesion,
since phorbol ester … Regulated expression and binding of three VLA (B1) integrin receptors on …

… cells through very late activation antigen-4 (VLA-4). Their binding of extracellular matrix …
or by protein kinase C stimulation by phorbol ester; staurosporine reduced binding, while …

… GMCSF or IL-1P, as well as phorbol esters or retinoic acid, which induce all61 expression
on endothelial cells [5], failed to induce a1@1 on monocytes (data not shown). Conversely, IFN…

… of VLA-4 to diminish, and also caused VLA-4 to become unresponsive to phorbol ester …
Results recently obtained for another b1 integrin (VLA-4) have also suggested that a chain …

… Phorbol ester and Mn2+, which have been shown to regulate … on MB1.1 and MB1.2 binding
to VLA-/31 integrin subunit. … human VLA integrins,"' but relatively few The expression of VLA-…

… VLA-4 molecules. Our results demonstrate that a short pulse of activation with phorbol esters
… expression of VLA-4, supporting the first hypothesis of a qualitative change undergone by …

… C agonist phorbol-12-myristate-13-acetate (PMA). The relative roles of β1 and β2 integrins
… Expression of VLA-4 on eosinophils decreases in patients with eosinophilia. Int Arch Allergy …

… VLA-4-mediated binding to its ligands. After either JY or JY-beta 1 cells were stimulated for
15 min with the phorbol ester … only -38% 1 and fibronectin), B1-positiveJY cells showed a high …

… The involvement of α M β 2 and α 5 β 1 in … -α 5 β 1 but not by anti-α M β 2 . These findings
identify Glu-Pg as an adhesive ligand for integrins α M β 2 and α 5 β 1 and suggest that α 5 β 1 …

… Our data suggest that cytokines GM-CSF and IL-3 specifically stimulate B1 integrin function
via an "… Phorbol ester modulation of integrin-mediated cell adhesion: a postreceptor event. …