TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

D Sun, J Wang, Y Han, X Dong, J Ge… - Nucleic acids …, 2021 - academic.oup.com
… We will maintain the web resources regularly to integrate new datasets. We will also
provide … of the TISCH web resource will benefit the broader cancer research community. …

Comprehensive benchmarking and integration of tumor microenvironment cell estimation methods

A Jiménez-Sánchez, O Cast, ML Miller - Cancer Research, 2019 - AACR
… We provide a Web resource to interactively explore the benchmark results and an objective
evaluation to help researchers select the most robust and accurate method to further …

Spatial heterogeneity in the tumor microenvironment

Y Yuan - Cold Spring Harbor perspectives in …, 2016 - perspectivesinmedicine.cshlp.org
… We focus on studies of immune infiltrate and tumor resource distribution, and highlight
statistical approaches for addressing the emerging challenges based on these new approaches. …

Tumor microenvironment

B Arneth - Medicina, 2019 - mdpi.com
… Aim: This study aims to explore the concept of the tumor microenvironment by conducting
a critical review of previous studies on the topic. Materials and Methods: This review relies on …

The web-based portal SpatialTME integrates histological images with single-cell and spatial transcriptomics to explore the tumor microenvironment

J Shi, X Wei, Z Xun, X Ding, Y Liu, L Liu, Y Ye - Cancer Research, 2024 - AACR
… The tumor microenvironment (TME) represents a complex network in which tumor cells …
can be a valuable resource to explore the tumor spatial microenvironment (TSME) and …

Computational approaches for characterizing the tumor immune microenvironment

CC Liu, CB Steen, AM Newman - Immunology, 2019 - Wiley Online Library
… the immune and stromal elements that comprise the tumor microenvironment (TME). Evaluating
the … Finally, we highlight several publicly available resources and discuss outstanding …

Network dynamics in the tumor microenvironment

H Bolouri - Seminars in cancer biology, 2015 - Elsevier
… of many intuitive web-based and menu-driven computational biology resources, and this …
Perhaps because of the arrival of these resources, we are also at a turning point in cancer …

TIGER: a web portal of tumor immunotherapy gene expression resource

Z Chen, Z Luo, D Zhang, H Li, X Liu… - Genomics …, 2023 - academic.oup.com
… Recent explosively growing single-cell transcriptome studies have provided a better
understanding of immune cell profiles in the tumor microenvironment (TME) before and after …

[HTML][HTML] Targeting the tumor microenvironment

PA Kenny, GY Lee, MJ Bissell - … in bioscience: a journal and virtual …, 2007 - ncbi.nlm.nih.gov
… an excellent target for microenvironment targeted therapy. … being synthesized in the breast
tumor microenvironment by a “… microenvironment resulting in strong efficacy against tumors

Identification of cancer hub gene signatures associated with immune-suppressive tumor microenvironment and ovatodiolide as a potential cancer immunotherapeutic …

JH Chen, ATH Wu, B Lawal, DTW Tzeng, JC Lee… - Cancers, 2021 - mdpi.com
… expressed in the TME rather than in the tumor cells; our results suggested that these cancer
hub … and immunosuppressive cells from the tumor microenvironment into the tumor tissues. …