Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations

LG de Almeida Chuffa, PP Freire… - Journal of Molecular …, 2022 - Springer
… The risk of severe COVID-19 increases with age as older … coronavirus 2 (SARS-CoV-2)
interacts with blood components during aging. We investigated the whole blood transcriptome

High-density blood transcriptomics reveals precision immune signatures of SARS-CoV-2 infection in hospitalized individuals

JW Prokop, NL Hartog, D Chesla, W Faber… - Frontiers in …, 2021 - frontiersin.org
Whole blood transcriptomics provides patient-level insights for immune activation,
immune repertoire, and secondary infections that can further guide precision treatment. …

A blood RNA transcriptome signature for COVID-19

PKW Kwan, GB Cross, CM Naftalin, BA Ahidjo… - BMC medical …, 2021 - Springer
… We examined the whole blood gene expression profile in patients with COVID-19 disease to
assess … ; and whether the transcriptome varies according to clinical disease manifestations. …

Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection

PP Sfikakis, KM Verrou… - Frontiers in …, 2021 - frontiersin.org
… associated with SARS-CoV-2 infection (52). To our knowledge, this is the first whole blood
genome-… who either experienced a clinical SARS-CoV-2 infection or an entirely asymptomatic …

[HTML][HTML] Detection of SARS-CoV-2 genome and whole transcriptome sequencing in frontal cortex of COVID-19 patients

S Gagliardi, ET Poloni, C Pandini, M Garofalo… - Brain, Behavior, and …, 2021 - Elsevier
… of SARS-CoV-2 in the brain of elderly patients died of COVID-19 and the possible effect of
SARS-CoV-2 infection on transcriptomic profile in frontal cortex comparing COVID-19 patients …

Machine learning‐driven blood transcriptome‐based discovery of SARSCoV2 specific severity biomarkers

P Krishnamoorthy, AS Raj… - Journal of Medical …, 2023 - Wiley Online Library
… We selected only the whole blood transcriptome data set … SARS-CoV-2 infection, we
selected one data set, GSE157103, that profiled whole blood leukocytes samples of SARS-CoV-2

A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patients

A Sadanandam, T Bopp, S Dixit, DJHF Knapp… - Cell death …, 2020 - nature.com
… The spread of COVID-19, a disease caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), has led to the current global pandemic with already millions of people …

Identifying novel host-based diagnostic biomarker panels for COVID-19: a whole-blood/nasopharyngeal transcriptome meta-analysis

S Maleknia, MJ Tavassolifar, F Mottaghitalab… - Molecular …, 2022 - Springer
… In order to detect similarities and differences in gene expression patterns between two
types of SARS-COV-2-infected tissues, we compared two sets of DEGs between COVID-19

Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community

HK Lee, L Knabl, L Pipperger, A Volland, PA Furth… - Scientific reports, 2021 - nature.com
… In summary, whole blood transcriptomes identified individual immune profiles within a
community population and showed that asymptomatic infection within a super-spreading event …

Blood transcriptomics reveal persistent SARS-CoV-2 RNA and candidate biomarkers in Long COVID patients

SM Menezes, M Jamoulle, MP Carletto, B Van Holm… - medRxiv, 2024 - medrxiv.org
… 1A), we also performed qualitative analysis of each SARS-CoV-2 transcript as well as total
blood viral load, comparing the frequency of positive (above cut-off, Fig. 2A) and negative …