Genome‐wide association studies on the phyllosphere microbiome: embracing complexity in host–microbe interactions

K Beilsmith, MPM Thoen, B Brachi, AD Gloss… - The Plant …, 2019 - Wiley Online Library
studies in their own plant systems. We argue that perspectives on how plant–microbe interactions
… or community-level interactions, on whether the interacting microbes are characterized …

Microbiome-wide association studies link dynamic microbial consortia to disease

JA Gilbert, RA Quinn, J Debelius, ZZ Xu, J Morton… - Nature, 2016 - nature.com
… distribution, which leads to large numbers of negative correlations and induces a … microbial
interactions that are linked to disease, including beneficial and harmful networks of microbes

[HTML][HTML] Genome-wide association studies in plant pathosystems: toward an ecological genomics approach

C Bartoli, F Roux - Frontiers in plant science, 2017 - frontiersin.org
… plants or in pathogenic microorganisms (bacteria, fungi and … identification of genes interacting
between genomes of both … molecular landscape underlying plant - microbe interactions. …

[HTML][HTML] Microbial genome-wide association studies: lessons from human GWAS

RA Power, J Parkhill, T De Oliveira - Nature reviews genetics, 2017 - nature.com
… Genome-wide association studies (GWAS) have been highly successful in the analyses …
microbial interactions would help to identify which host proteins the microorganism is interacting

[HTML][HTML] Genome-wide association study of Arabidopsis thaliana leaf microbial community

MW Horton, N Bodenhausen, K Beilsmith… - Nature …, 2014 - nature.com
… Identifying the factors that influence the outcome of host–microbial interactions is critical to
… Genome-wide association studies (GWAS) suggest that plant loci responsible for defense …

[HTML][HTML] Current affairs of microbial genome-wide association studies: approaches, bottlenecks and analytical pitfalls

JE San, S Baichoo, A Kanzi, Y Moosa… - Frontiers in …, 2020 - frontiersin.org
… on human and microbial genome-wide association studies, 1993–… -wide Association Studies
and “Microbial Genome-wide … a genetic variant matrix of interaction effects which is created …

[HTML][HTML] Host and microbiome genome-wide association studies: current state and challenges

D Awany, I Allali, S Dalvie, S Hemmings… - Frontiers in …, 2019 - frontiersin.org
… used to elucidate the interaction of host … interaction between host genetics and microbial
communities. In this paper, we review recent studies investigating host–microbiome interactions

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

L Jostins, S Ripke, RK Weersma, RH Duerr… - Nature, 2012 - nature.com
… Genome-wide association studies and subsequent meta-… and ulcerative colitis genome-wide
association scans, followed by … We identify 71 new associations, for a total of 163 IBD loci, …

[HTML][HTML] Network mapping of root–microbe interactions in Arabidopsis thaliana

X He, Q Zhang, B Li, Y Jin, L Jiang, R Wu - npj Biofilms and …, 2021 - nature.com
… From these data, genome-wide association studies (GWAS) have been developed to
systematically characterize the genetic underpinnings of microbiota-host associations in plants 15,…

[HTML][HTML] Recent perspectives on gene-microbe interactions determining predisposition to otitis media

R Mittal, SV Sanchez-Luege, SM Wagner, D Yan… - Frontiers in …, 2019 - frontiersin.org
studies, followed by linkage studies, candidate gene approaches, and genome-wide association
studies … ) sequencing, microbial quantitative trait loci (mbQTL), and microbial genome-…