… Conceptually similar to this approach, our study establishes particle uptake as a method to
… Particle uptake patterns are expected to provide an additional layer of information related to …

… the cellular uptake and cytotoxicity of targeted and nontargeted DOX-loaded NPs in drug-resistant …
The drug loading of the conjugated particles was lower than for their nonconjugated …

… -NPs, including particle size, zeta potential, particle morphology and Cur release … uptake
and cytotoxicity of targeted and nontargeted Cur-loaded NPs in drug resistant (KB-V1) and drug …

… resistance to the free drug because of improved cellular uptake rates, and that dose response
curves to nanocarrier mediated drug delivery are equivalent to those for free-drug, but “…

… For example, LDL particles that are engulfed through LDLR are transferred to lysosomes
for … In summary, Pt-based drug resistance is an important event in the therapeutics of a wide …

… similar trends in rate and preference of particle uptake. … Particle uptake by epithelial cells
and macrophages differs regarding the size. Only macrophages can efficiently ingest particles >…

… -MSNP) were retained in the particles that localized in the peri-… particle uptake compared
to the unmodified MSNP. However, while much of the drug remained confined to the particles, …

… the nuclear uptake of nanodrugs is mainly attributed to small particle size, thus avoiding
complicated NLS modification processes and maintaining the valid occupancy of drug-loading …

… to overcome this common mechanism of drug resistance in cancer cells. Doxorubicin
nanocarriers (DNC) increased effective drug uptake in drug-resistant ovarian cells. Mechanistically, …

… non-specific cellular uptake, and poor tumor vascularity that limits drug accessing to tumor
tissues [2]. … A particle diameter between 50 to 150nm is optimal for drug retention and tumor ex…