Objective: The ability of cells to collectively move is essential in various biological contexts
including cancer metastasis. In this paper, we propose an automatic video analysis tool to …

Cell motility is the brilliant result of cell status and its interaction with close environments. Its
detection is now possible, thanks to the synergy of high-resolution camera sensors, time …

Cell-cell interactions are an observable manifestation of underlying complex biological
processes occurring in response to diversified biochemical stimuli. Recent experiments with …

We describe a novel method to achieve a universal, massive, and fully automated analysis
of cell motility behaviours, starting from time-lapse microscopy images. The approach was …

Cell motility varies according to intrinsic features and microenvironmental stimuli, being a
signature of underlying biological phenomena. The heterogeneity in cell response, due to …

Background Cell motility is a critical parameter in many physiological as well as
pathophysiological processes. In time-lapse video microscopy, manual cell tracking remains …

Background In vitro cell observation has been widely used by biologists and
pharmacologists for screening molecule-induced effects on cancer cells. Computer-assisted …

Tumor heterogeneity is a primary factor that contributes to treatment failure. Predictive tools,
capable of classifying cancer cells based on their functions, may substantially enhance …

Cell behaviors are reflections of intracellular tension dynamics and play important roles in
many cellular processes. In this study, temporal variations in cell geometry and cell motion …

Motivation Time-lapse microscopy is a powerful technique that relies on images of live cells
cultured ex vivo that are captured at regular intervals of time to describe and quantify their …