Cancer phenotypes are often associated with changes in the mechanical states of cells and
their microenvironments. Numerous studies have established correlations between cancer …

Uptake of particles by cells involves various natural mechanisms that are essential for their
biological functions. The same mechanisms are used in the engulfment of synthetic colloidal …

Cells continuously exert forces on their environment and respond to changes in mechanical
forces by altering their behaviour. Many pathologies such as cancer and fibrosis are …

Nanoparticle (NP)-bioconjugates hold great promise for more sensitive disease diagnosis
and more effective anticancer drug delivery compared with existing approaches. A critical …

Endocytosis is a normal process in living cells, often used to internalize drug-containing
particles and probes for intracellular mechanics. The cell type, and especially malignancy …

Mechanical forces play an important role in the regulation of cellular behavior and
physiological processes including adhesion, migration, proliferation, tissue repair …

Cell mechanics provides insights in cell responses to external stress, which is an important
parameter known to influence a variety of cell functions. Understanding the interdependence …

Metastasis requires the penetration of cancer cells through tight spaces, which is mediated
by the physical properties of the cells as well as their interactions with the confined …

Increased tissue stiffness is a classic characteristic of solid tumors. One of the major
contributing factors is increased density of collagen fibers in the extracellular matrix (ECM) …

The mechanical properties of living cells reflect their physiological and pathological state. In
particular, cancer cells undergo cytoskeletal modifications that typically make them softer …