Irregular biomechanics are a hallmark of cancer biology subject to extensive study. The
mechanical properties of a cell are similar to those of a material. A cell's resistance to stress …

Editorial Babahosseini, Strobl & Agah screening of therapeutic agents that target
cytoskeleton dysfunction. One application of this approach is the determination whether the …

The main cause of mortality among cancer patients is metastatic disease. Metastasis
develops from cancer cells that invade the stromal tissue and intravasate the circulatory or …

High-throughput analysis of cancer cell dissemination and its control by extrinsic and
intrinsic cellular factors is hampered by the lack of adequate and efficient analytical tools for …

Nanoparticle (NP)-bioconjugates hold great promise for more sensitive disease diagnosis
and more effective anticancer drug delivery compared with existing approaches. A critical …

Simple Summary Detection of circulating tumor cells (CTCs) in the blood of cancer patients
is a challenging issue, since they adapt to the biochemical and physical landscape of the …

Cellular plasticity refers to the ability of cells to change their identity or behavior, which can
be advantageous in some cases (eg, tissue regeneration) but detrimental in others (eg …

Cancer is a multi-step process where normal cells become transformed, grow, and may
disseminate to establish new lesions within the body. In recent years, the physical properties …

Major progress in the understanding and treatment of cancer have tremendously improved
our knowledge of this complex disease and improved the length and quality of patients' …

Abstract Preclinical Research Spatial and temporal dynamics of cancer, studied with
physical science approaches at critical transition points of the disease can provide insight …