Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

CM Woo, Z Li, EK Paulson… - Proceedings of the …, 2016 - National Acad Sciences
(–)-Lomaiviticin A (1) is a complex antiproliferative metabolite that inhibits the growth of
many cultured cancer cell lines at low nanomolar–picomolar concentrations.(–)-Lomaiviticin …

Structural basis for DNA cleavage by the potent antiproliferative agent (-)-lomaiviticin A

CM Woo, Z Li, EK Paulson… - Proceedings of the …, 2016 - pubmed.ncbi.nlm.nih.gov
(-)-Lomaiviticin A (1) is a complex antiproliferative metabolite that inhibits the growth of many
cultured cancer cell lines at low nanomolar-picomolar concentrations.(-)-Lomaiviticin A (1) …

Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

CM Woo, Z Li, EK Paulson, SB Herzon - … Academy of Sciences of the United …, 2016 - JSTOR
(–)-Lomaiviticin A (1) is a complex antiproliferative metabolite that inhibits the growth of
many cultured cancer cell lines at low nanomolar–picomolar concentrations.(–)-Lomaiviticin …

Structural basis for DNA cleavage by the potent antiproliferative agent (-)-lomaiviticin A.

CM Woo, Z Li, EK Paulson… - Proceedings of the …, 2016 - europepmc.org
Results We first performed fluorescent intercalator displacement (FID) assays (23–25) to
probe the interaction and binding preferences of (–)-lomaiviticins A–C (1–3) and (–) …

Structural basis for DNA cleavage by the potent antiproliferative agent (-)-lomaiviticin A

CM Woo, Z Li, EK Paulson… - Proceedings of the …, 2016 - ui.adsabs.harvard.edu
DNA is a canonical target for chemotherapeutic intervention, and several DNA-reactive
natural products are in clinical use. An understanding of the mode of DNA binding of these …

Structural basis for DNA cleavage by the potent antiproliferative agent (-)-lomaiviticin A

CM Woo, Z Li, EK Paulson, SB Herzon - Proceedings of the National …, 2016 - hero.epa.gov
Lomaiviticin A (1) is a complex antiproliferative metabolite that inhibits the growth of many
cultured cancer cell lines at low nanomolar-picomolar concentrations.(-)-Lomaiviticin A (1) …

[HTML][HTML] Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

CM Woo, Z Li, EK Paulson… - Proceedings of the …, 2016 - ncbi.nlm.nih.gov
Results We first performed fluorescent intercalator displacement (FID) assays (23–25) to
probe the interaction and binding preferences of (–)-lomaiviticins A–C (1–3) and (–) …

Structural basis for DNA cleavage by the potent antiproliferative agent (–)-lomaiviticin A

CM Woo, Z Li, EK Paulson, SB Herzon - Proceedings of the National …, 2016 - cir.nii.ac.jp
抄録< jats: p>(–)-Lomaiviticin A (1) is a complex antiproliferative metabolite that inhibits the
growth of many cultured cancer cell lines at low nanomolar–picomolar concentrations.(–) …