Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library

S Park, J Fan, S Chamakuri… - Journal of Medicinal …, 2023 - ACS Publications
β-Lactamase enzymes hydrolyze and thereby provide bacterial resistance to the important β-
lactam class of antibiotics. The OXA-48 and NDM-1 β-lactamases cause resistance to the …

Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.

S Park, J Fan, S Chamakuri, M Palaniappan… - Journal of Medicinal …, 2023 - europepmc.org
β-Lactamase enzymes hydrolyze and thereby provide bacterial resistance to the important β-
lactam class of antibiotics. The OXA-48 and NDM-1 β-lactamases cause resistance to the …

Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library

S Park, J Fan, S Chamakuri… - Journal of …, 2024 - pubmed.ncbi.nlm.nih.gov
β-Lactamase enzymes hydrolyze and thereby provide bacterial resistance to the important β-
lactam class of antibiotics. The OXA-48 and NDM-1 β-lactamases cause resistance to the …