Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods

Y Wei, J Li, Z Chen, F Wang, W Huang, Z Hong… - European journal of …, 2015 - Elsevier
The HIV-1 protease has proven to be a crucial component of the HIV replication machinery
and a reliable target for anti-HIV drug discovery. In this study, we applied an optimized …

Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods

Y Wei, J Li, Z Chen, F Wang… - European journal …, 2015 - pubmed.ncbi.nlm.nih.gov
The HIV-1 protease has proven to be a crucial component of the HIV replication machinery
and a reliable target for anti-HIV drug discovery. In this study, we applied an optimized …

Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods.

Y Wei, J Li, Z Chen, F Wang, W Huang… - European Journal of …, 2015 - europepmc.org
The HIV-1 protease has proven to be a crucial component of the HIV replication machinery
and a reliable target for anti-HIV drug discovery. In this study, we applied an optimized …

Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods

Y Wei, J Li, Z Chen, F Wang, W Huang, Z Hong… - European Journal of …, 2015 - infona.pl
The HIV-1 protease has proven to be a crucial component of the HIV replication machinery
and a reliable target for anti-HIV drug discovery. In this study, we applied an optimized …