Kv1. 4 channel block by quinidine: evidence for a drug‐induced allosteric effect

S Wang, MJ Morales, YJ Qu, GCL Bett… - The Journal of …, 2003 - Wiley Online Library
We studied quinidine block of Kv1. 4ΔN, a K+ channel lacking N‐type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect.

S Wang, MJ Morales, YJ Qu, GC Bett… - The Journal of …, 2003 - europepmc.org
We studied quinidine block of Kv1. 4DeltaN, a K (+) channel lacking N-type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

[HTML][HTML] Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect

S Wang, MJ Morales, YJ Qu, GCL Bett… - The Journal of …, 2003 - ncbi.nlm.nih.gov
We studied quinidine block of Kv1. 4ΔN, a K+ channel lacking N-type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect

S Wang, MJ Morales, YJ Qu… - The Journal of …, 2003 - pubmed.ncbi.nlm.nih.gov
We studied quinidine block of Kv1. 4DeltaN, a K (+) channel lacking N-type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect.

S Wang, MJ Morales, YJ Qu, GC Bett, HC Strauss… - J Physiol, 2003 - xenbase.org
We studied quinidine block of Kv1. 4DeltaN, a K (+) channel lacking N-type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

[PDF][PDF] Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect

S Wang, MJ Morales, YJ Qu, GCL Bett, HC Strauss… - J Physiol, 2003 - academia.edu
Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel so rapidly it
overlapped with activation. This rapid open channel block was reduced (non-additively) by …

Kv1. 4 channel block by quinidine: evidence for a drug‐induced allosteric effect

S Wang, MJ Morales, YJ Qu, GCL Bett… - The Journal of …, 2003 - cir.nii.ac.jp
抄録< jats: p> We studied quinidine block of Kv1. 4ΔN, a K< jats: sup>+</jats: sup> channel
lacking N‐type inactivation, expressed in< jats: italic> Xenopus</jats: italic> ooctyes. Initially …

Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect.

S Wang, MJ Morales, YJ Qu, GC Bett, HC Strauss… - J Physiol, 2003 - xenbase.org
We studied quinidine block of Kv1. 4DeltaN, a K (+) channel lacking N-type inactivation,
expressed in Xenopus ooctyes. Initially, quinidine intracellularly blocked the open channel …

[引用][C] Kv1. 4 channel block by quinidine: evidence for a drug-induced allosteric effect

S WANG, MJ MORALES, YJ QU, GCL BETT… - Journal of …, 2003 - Blackwell