Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction

CH Chiang, T Wymore… - Proceedings of the …, 2023 - National Acad Sciences
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing
complementary selectivity profiles enables divergent synthetic strategies, but is challenging …

[HTML][HTML] Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction

CH Chiang, T Wymore, AR Benítez… - Proceedings of the …, 2023 - ncbi.nlm.nih.gov
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing
complementary selectivity profiles enables divergent synthetic strategies, but is challenging …

Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction

CH Chiang, T Wymore… - Proceedings of the …, 2023 - ui.adsabs.harvard.edu
Biocatalysts provide powerful tools for target-oriented synthesis. However, it is difficult for
biocatalytic reactions to achieve complementary selectivity and afford different …

Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction.

CH Chiang, T Wymore, A Hussain, JL Smith… - Proceedings of the …, 2023 - europepmc.org
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing
complementary selectivity profiles enables divergent synthetic strategies, but is challenging …

Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction

CH Chiang, T Wymore, AR Benítez… - Proceedings of the …, 2023 - pubmed.ncbi.nlm.nih.gov
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing
complementary selectivity profiles enables divergent synthetic strategies, but is challenging …