Allosteric inhibition of SHP2 stimulates antitumor immunity by transforming the immunosuppressive environment

E Quintana, CJ Schulze, DR Myers, TJ Choy, K Mordec… - Cancer research, 2020 - AACR
The protein tyrosine phosphatase SHP2 binds to phosphorylated signaling motifs on
regulatory immunoreceptors including PD-1, but its functional role in tumor immunity is …

Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment

E Quintana, CJ Schulze, DR Myers… - Cancer …, 2020 - pubmed.ncbi.nlm.nih.gov
The protein tyrosine phosphatase SHP2 binds to phosphorylated signaling motifs on
regulatory immunoreceptors including PD-1, but its functional role in tumor immunity is …

Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment.

E Quintana, CJ Schulze, DR Myers, TJ Choy… - Cancer …, 2020 - europepmc.org
The protein tyrosine phosphatase SHP2 binds to phosphorylated signaling motifs on
regulatory immunoreceptors including PD-1, but its functional role in tumor immunity is …