Targeted covalent enzyme inhibitors

MC Noe, AM Gilbert - Annual Reports in Medicinal Chemistry, 2012 - Elsevier
Targeted covalent enzyme inhibition is experiencing resurgence as a medicinal chemistry
design strategy. Targeted covalent inhibitors exhibit slow target offset, increased binding …

[引用][C] Targeted Covalent Enzyme Inhibitors

MC Noe, AM Gilbert - Annual reports in medicinal chemistry, 2012 - dialnet.unirioja.es

Targeted Covalent Enzyme Inhibitors

MC Noe, AM Gilbert - Annual Reports in Medicinal Chemistry, 2012 - books.google.com
Small molecule drugs exert their pharmacological effects through binding to biomolecular
targets, thereby modulating their activity (in the case of enzymes) or downstream signaling …