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Atomic-resolution prediction of degrader-mediated ternary complex structures by combining molecular simulations with hydrogen deuterium exchange

T Dixon, D MacPherson, B Mostofian, T Dauzhenka… - Biorxiv, 2021 - biorxiv.org
Targeted protein degradation (TPD) has emerged as a powerful approach in drug discovery
for removing (rather than inhibiting) proteins implicated in diseases. A key step in this …
被引用次数：12 相关文章

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T Dixon, D MacPherson, B Mostofian, T Dauzhenka… - 2021 - europepmc.org
Targeted protein degradation (TPD) has emerged as a powerful approach in drug discovery
for removing (rather than inhibiting) proteins implicated in diseases. A key step in this …

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T Dixon, D MacPherson, B Mostofian, T Dauzhenka… - 2022 - researchsquare.com
Targeted protein degradation (TPD) has emerged as a powerful approach for removing
(rather than inhibiting) proteins implicated in diseases. A key step in TPD is the formation of …

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T Dixon, D MacPherson, B Mostofian, T Dauzhenka… - 2022 - europepmc.org
Targeted protein degradation (TPD) has emerged as a powerful approach for removing
(rather than inhibiting) proteins implicated in diseases. A key step in TPD is the formation of …