First-in-human trial of novel oral PARP inhibitor BMN 673 in patients with solid tumors.

JS De Bono, LA Mina, M Gonzalez, NJ Curtin, E Wang… - 2013 - ascopubs.org
2580 Background: BMN 673 is the most potent and specific inhibitor of PARP1/2 in clinical
development (IC50< 1nM). In tumors genetically dependent on DNA repair by homologous …

[引用][C] First-in-human trial of novel oral PARP inhibitor BMN 673 in patients with solid tumors

B De, LA Mina, M Gonzalez, NJ Curtin… - 2013 ASCO Annual …, 2013 - eprints.ncl.ac.uk
First-in-human trial of novel oral PARP inhibitor BMN 673 in patients with solid tumors - ePrints -
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