Coronary artery disease-associated genetic variants and biomarkers of inflammation

MK Christiansen, SB Larsen, M Nyegaard… - PloS one, 2017 - journals.plos.org
… risk associated with all the genetic variants. A multiple linear regression … genetic variants
or the combined effect of all variants were associated with the five inflammatory biomarkers

Inflammation-related risk loci in genome-wide association studies of coronary artery disease

C Mauersberger, H Schunkert, HB Sager - Cells, 2021 - mdpi.com
… While this study has several weaknesses, IL-5 seems unlikely to be a relevant biomarker for
… This study disclosed several gene variants, attributed to the PRKCE, CFTR, PRXL2A, TRIM5…

[PDF][PDF] Novel genetic risk factors in coronary artery disease and related biomarkers

S Ruotsalainen - 2022 - helda.helsinki.fi
… using information on the genetic variants in close proximity. … traditional CAD biomarkers with
Lp(a) and inflammation we … us to detect disease associated genetic variants that would have …

Rheumatoid arthritis: genetic variants as biomarkers of cardiovascular disease

L Rodriguez-Rodriguez, R Lopez-Mejias… - Current …, 2015 - ingentaconnect.com
… Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with … have
been associated with a higher risk of coronary artery disease in the general population [207, …

Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants

S Sayols-Baixeras, C Lluís-Ganella… - … of clinical genetics, 2014 - Taylor & Francis
… CAD is a complex chronic inflammatory disease, … , likely disease-causing, disease-associated,
functional but not associated … Several biomarkers, including genetic variants, have been …

Identifying novel gene variants in coronary artery disease and shared genes with several cardiovascular risk factors

M LeBlanc, V Zuber, BK Andreassen… - Circulation …, 2016 - Am Heart Assoc
… Genome-wide association studies (GWAS) in CAD have identified a total of 46 genetic
variants reaching genome-wide significance for CAD. However, the identified genetic variants

[HTML][HTML] Implications of genetic polymorphisms in inflammation-induced atherosclerosis

J Shanker, VV Kakkar - The open cardiovascular medicine journal, 2010 - ncbi.nlm.nih.gov
… of specific biomarkers of inflammation that collectively contribute to the disease-associated
risk. In … 4 (TNFSF4) gene variation showed limited association of these variants with CVD in …

Unraveling new therapeutic targets of coronary artery disease by genetic approaches

SE Lee, HS Kim - Circulation journal, 2014 - jstage.jst.go.jp
genetic variants and environmental factors, and genetic … aiming to identify disease-associated
genetic loci. Furthermore, … than to affect the level of the biomarker of intereset. If it does, …

Biomarkers and genetics in peripheral artery disease

S Hazarika, BH Annex - Clinical chemistry, 2017 - academic.oup.com
… A causal role of inflammatory biomarkers with development and… associations of circulating
inflammatory markers with disease … Leg symptoms in peripheral arterial disease: associated

[图书][B] Genetic control of selected inflammatory markers in families with early onset coronary artery disease

B Suktitipat - 2010 - search.proquest.com
… Background: Inflammatory biomarkers in atherosclerosis … Additional genetic variants with
highly suggestive results (p < 1×… to estimate the risk of disease associated with each genotype. …