[HTML][HTML] Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases

K Das, S Paul, T Mukherjee, A Ghosh, A Sharma… - Cells, 2023 - mdpi.com
… This suggests that EV-based therapies may hold promise for the treatment of inflammatory
diseases, providing a targeted and personalized approach. EVs are safe, are efficient, and …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles: An emerging diagnostic and therapeutic biomolecules for neurodegenerative disabilities

M Kandeel, MA Morsy, KM Alkhodair, S Alhojaily - Biomolecules, 2023 - mdpi.com
… It holds promise for the treatment of ischemic diseases, tissue … challenges in standardization,
scalability, payload loading, storage, and targeting [235,236]. However, the future prospects

[HTML][HTML] Multiplexed strategies toward clinical translation of extracellular vesicles

J Song, B Song, L Yuan, G Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
… technology, this method holds great promise in the clinic. Based … A significant challenge of
using these plants as donors is the … EV-based therapy has a bright prospect attributed to the …

[HTML][HTML] Therapeutic potential of human stem cell-derived extracellular vesicles in idiopathic pulmonary fibrosis

KS Lee, SH Yeom, MK Kim, CH Woo, YC Choi… - Extracellular …, 2024 - Elsevier
… MSC-based therapy is promising for the treatment of chronic … However, MSC-based therapy
should consider safety issues, … ) as a treatment for respiratory diseases, including COVID-19, …

[HTML][HTML] MSC-derived exosomes carrying a cocktail of exogenous interfering RNAs an unprecedented therapy in era of COVID-19 outbreak

M Jamalkhah, Y Asaadi, M Azangou-Khyavy… - Journal of Translational …, 2021 - Springer
COVID-19 treatment. Thereafter, the promise of RNA interference (RNAi) -based gene therapy
… study has been conducted from this perspective. Seven candidate miRNAs were revealed …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
… hold significant promise in formulating innovative therapeutic … to support their investigation
in future clinical trials, focusing on their … This section addresses issues concerning machinery …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles as idiopathic pulmonary fibrosis microenvironment targeted delivery

L Sang, X Guo, H Fan, J Shi, S Hou, Q Lv - Cells, 2022 - mdpi.com
treatment of COVID-19 together with pulmonary fibrosis is currently being recruited (NCT05191381)
[114]. In summary, the MSC-EVs therapy … needs to face many challenges. Here, we …

Technological advances towards extracellular vesicles mass production

A Grangier, J Branchu, J Volatron, M Piffoux… - Advanced Drug Delivery …, 2021 - Elsevier
… these EV-based therapies, many challenges remain such as … cells (MSCs), hold many
promises as they have been regarded as … Notably, the active search for COVID-19 treatments also …

[HTML][HTML] Extracellular vesicles as delivery systems in disease therapy

MA Picon, L Wang, A Da Fonseca Ferreira… - International journal of …, 2023 - mdpi.com
… system for the mRNA COVID-19 vaccine. Recently, different … the protein composition matches
target expectations [7]. Researchers … therapeutic agents has shown promise to improve the …

[HTML][HTML] Recent advances in the use of extracellular vesicles from adipose-derived stem cells for regenerative medical therapeutics

S Yang, Y Sun, C Yan - Journal of Nanobiotechnology, 2024 - ncbi.nlm.nih.gov
… in treating chronic cough after COVID-19 Long COVID-19 … for the treatment of COVID-19
COVID-19 pneumonia … promise as a therapeutic agent within the field of regenerative medicine. …