[HTML][HTML] First results of phase 3 trial of RTS, S/AS01 malaria vaccine in African children

RTS, S Clinical Trials Partnership - New England Journal of …, 2011 - Mass Medical Soc
… ,11 and provided protection against severe malaria.Here, we report the initial results of
an ongoing phase 3 trial being conducted at 11 centers in 7 African countries (Fig. 1 in the …

[HTML][HTML] A phase 3 trial of RTS, S/AS01 malaria vaccine in African infants

RTS, S Clinical Trials Partnership - New England Journal of …, 2012 - Mass Medical Soc
… control group6 14 months after the first dose of vaccine administered in children 6 to 12 weeks
of … First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. N Engl J …

… safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

S Rts - Lancet, 2015 - thelancet.com
… Herein, we report the final results from the same trial, including the efficacy of a booster
dose. … First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children. …

[HTML][HTML] … of the RTS, S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African …

RTS, S Clinical Trials Partnership (2014) - PLoS medicine, 2014 - journals.plos.org
… This analysis combines the first and second groups (referred to as the RTS,S/AS01 group)
and … >0 parasites/mm 3 ) was used for the evaluation of the impact of RTS,S/AS01 on clinical …

… of severe malaria following RTS, S/AS01 vaccination in children and infants in Africa: an open-label 3-year extension study of a phase 3 randomised controlled trial

H Tinto, W Otieno, S Gesase, H Sorgho… - The Lancet Infectious …, 2019 - thelancet.com
Results from a previous phase 3 study showed efficacy of the … In the initial phase 3 study,
infants aged 6–12 weeks and children aged 5–17 months were randomly assigned (1:1:1) to …

[HTML][HTML] RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use

YY Syed - Drugs & Therapy Perspectives, 2022 - Springer
… In a phase 3 trial, RTS,S/AS01 showed vaccine efficacy … First results from large pilot
implementation in Africa show … from a phase 3 trial (NCT01148459) in children with WHO stage 1 …

Efficacy of phase 3 trial of RTS, S/AS01 malaria vaccine: the need for an alternative development plan

S Mahmoudi, H Keshavarz - Human vaccines & …, 2017 - Taylor & Francis
… In a phase 3 randomized, controlled trials in children and young infants at 11 African sites
from March 27, 2009, through … First results of phase 3 trial of RTS,S/AS01 malaria vaccine in …

[HTML][HTML] … of the RTS, S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

MT White, R Verity, JT Griffin, KP Asante… - The Lancet infectious …, 2015 - thelancet.com
African children aged 5–17 months and 6537 African infants aged 6–12 weeks at first vaccination,
… We assessed the effects of several covariates on anti-circumsporozoite antibody titres …

RTS, S/AS01E malaria vaccine induces IgA responses against CSP and vaccine-unrelated antigens in African children in the phase 3 trial

R Suau, M Vidal, R Aguilar, G Ruiz-Olalla… - Vaccine, 2021 - Elsevier
children (age 5–17 months old at first vaccination) from the RTS,S/AS01 E phase 3 clinical
trial who received 3 … that this could have an impact on protective immunity to malaria [35]. Little …

[HTML][HTML] Seasonal vaccination with RTS, S/AS01E vaccine with or without seasonal malaria chemoprevention in children up to the age of 5 years in Burkina Faso and …

A Dicko, JB Ouedraogo, I Zongo, I Sagara… - The Lancet Infectious …, 2024 - thelancet.com
… in infants and children in Africa: final results of a phase 3, … with RTS,S/AS01 E during the
first 3 years of the study, all of whom … recorded in the RTS,S/AS01 E phase 3 trial were chance …