Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - The Lancet, 2022 - thelancet.com
… , should the nirmatrelvir plus ritonavir be accessible and clinically appropriate. This study
shows real-world effectiveness of oral antivirals in reducing the mortality risk of community-…

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir against mortality, hospitalization, and in-hospital outcomes among community-dwelling, ambulatory …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - MedRxiv, 2022 - medrxiv.org
efficacy, our findings give support to current guidelines prioritizing nirmatrelvir/ritonavir use
over molnupiravir … Amid a pandemic wave of the Omicron variant, real-world effectiveness of …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir among COVID-19 community, highly vaccinated patients with high risk for severe disease: evidence …

D Paraskevis, M Gkova, K Mellou, G Gerolymatos… - medRxiv, 2023 - medrxiv.org
… recipients had a reduced risk for death (HR:0.34) and hospitalization (HR: 0.76), with mortality
risks to be consistently lower among elderly patients with early antiviral use [20]. In a study …

[HTML][HTML] Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence

I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
… trials and real-world studies investigating the efficacy of these … and real-world studies
have demonstrated the efficacy of … mortality, as demonstrated using clinical trials and real-world

[HTML][HTML] Determining and comparing the real-world effectiveness of molnupiravir and nirmatrelvir-ritonavir in patients hospitalized with COVID-19

YR Jang, Y Oh, JY Kim - Journal of Korean Medical Science, 2024 - ncbi.nlm.nih.gov
… use showed substantial clinical benefit, including a lower risk of all-cause mortality, in-…
should compare the effectiveness and safety of nirmatrelvir-ritonavir and molnupiravir. This …

Real-world effectiveness of oral antivirals for COVID-19

C Burdet, F Ader - The Lancet, 2022 - thelancet.com
plus ritonavir), whereas the effect on mortality was not … for molnupiravir, and not evaluable
for nirmatrelvir plus ritonavir … the efficacy of both antivirals in preventing all-cause mortality was …

Real-world Effectiveness of Molnupiravir and Nirmatrelvir/Ritonavir as Treatments for COVID-19 in Patients at High Risk

D Paraskevis, M Gkova, K Mellou… - The Journal of …, 2023 - academic.oup.com
… recipients exhibited a reduced risk of death (HR, 0.34) and hospitalization (HR, 0.76), with
mortality risks that were consistently lower among elderly patients and in response to early …

[HTML][HTML] Real-World Study on Effectiveness of Molnupiravir and NirmatrelvirRitonavir in Unvaccinated Patients with Chronic Respiratory Diseases with Confirmed …

WC Kwok, MF Tsoi, SHI Leung, CK Tsui, TCC Tam… - Viruses, 2023 - mdpi.com
… hospitalization and mortality by 89… Real-world studies have also suggested the benefits of
MOV and NMV-r. Early initiation of oral antivirals was associated with reduced risks of mortality

Effectiveness of molnupiravir and nirmatrelvirritonavir in hospitalized patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, AHY Mok, B Wang… - Annals of internal …, 2023 - acpjournals.org
molnupiravir or nirmatrelvirritonavir, this study aimed to assess the effectiveness of both
drugs in reducing mortality and … the real-world effectiveness of molnupiravir and nirmatrelvir–…

[HTML][HTML] The antiviral effect of nirmatrelvir/ritonavir during COVID-19 pandemic real-world data

V Petrakis, P Rafailidis, G Trypsianis, D Papazoglou… - Viruses, 2023 - mdpi.com
… their efficacy, such as molnupiravir and nirmatrelvir/ritonavir, … Treatment with
nirmatrelvir/ritonavir reduced the mortality or … Subtype analysis indicated an 88% reduction in …