α-Catenin localization and sarcomere self-organization on N-cadherin adhesive patterns are myocyte contractility driven

A Chopra, A Patel, AC Shieh, P A. Janmey, JY Kresh - 2012 - journals.plos.org
… study α-catenin since it has been shown to alter its expression and conformation relative to
cell-cell adhesion … role of α-catenin in the mechanosignaling complex of N-cadherin mediated …

[PDF][PDF] α-Catenin Localization and Sarcomere Self-Organization on N-Cadherin Adhesive Patterns Are Myocyte Contractility...

P Janmey, JY Kresh - 2012 - academia.edu
… Therefore, cells on ‘‘Y’’ shaped micro-pattern geometries provide an ideal model system to
… subcellular localization in response to variations in stress found at the N-cadherin adhesion

… and Dynamics of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) on Hydrogels with Spatially Patterned Laminin and N-Cadherin

KV Lane, LP Dow, EA Castillo, R Boros… - … Applied Materials & …, 2024 - ACS Publications
localized endogenous N-cadherin on the in vitro N-cadherin … to patterns, even if they did not
overlap either N-cadherin cap. … only single cells which had visible sarcomeres. While these …

Spatial Patterning of Laminin and N-Cadherin for Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs)

KV Lane, LP Dow, EA Castilloa, R Boros, SD Feinstein… - bioRxiv, 2023 - biorxiv.org
localized endogenous N-cadherin on the in vitro N-cadherin … -protein patterns would have
more highly organized sarcomeres … found that N-cadherin is important in sarcomere formation …

Switching of α-catenin from epithelial to neuronal type during lens epithelial cell differentiation

R Maddala, PV Rao - Investigative ophthalmology & visual …, 2017 - iovs.arvojournals.org
pattern of neuronal-specific α-catenin (αN-catenin) and its interaction with the N-cadherin–…
Both lens epithelium and fibers develop extensive cadherin-based cell–cell adhesive

Intercalated discs and arrhythmogenic cardiomyopathy

A Rampazzo, M Calore, J van Hengel… - Circulation …, 2014 - Am Heart Assoc
… -catenin (or plakoglobin) to α-catenin, which in turn binds via … the N-cadherin/αE-catenin
complex regulates sarcomeric … an autosomal-dominant pattern of inheritance with incomplete …

Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes

MR Salick, BN Napiwocki, J Sha, GT Knight… - Biomaterials, 2014 - Elsevier
… in sarcomere alignment relative to the long axis of the pattern. … These gap junctions localized
to both lateral and axial edges … sarcomere structure involve a combination of focal adhesion/…

[图书][B] Intercellular and extracellular adhesion signals control cardiac myocyte structural and functional remodeling: mechanosensing mediated by cadherin and …

A Chopra - 2012 - researchdiscovery.drexel.edu
αcatenin localization and sarcomere self-organization on N-cadherin adhesive patterns are
… also shown to be influenced by N-cadherin-mediated adhesion through the activation of the …

Multi-level Force-dependent Allosteric Enhancement of αE-catenin Binding to F-actin by Vinculin

NA Bax, A Wang, DL Huang, S Pokutta, WI Weis… - Journal of molecular …, 2023 - Elsevier
… , which binds to the cadherin cytoplasmic tail and to α-catenin, which in turn binds to F-actin3,
4 (… The actin cables in some epithelial tissues show clear sarcomeric organization, implying …

Striated myocyte structural integrity: Automated analysis of sarcomeric z-discs

TA Morris, J Naik, KS Fibben, X Kong… - PLoS computational …, 2020 - journals.plos.org
As sarcomeres produce the force necessary for contraction, assessment of sarcomere order …
The uniaxial force produced by sarcomeres is ideally perpendicular to their z-lines, which …