… , and thus its expression is downregulated through specific signaling mechanisms [64]. …
synthesizing enzymes, we also observed a slight upregulation on the TH gene in BC tissues…

… , in particular through β2 adrenergic receptor (β2-AR) signaling. … cell escape[82, 83] (Figure
2), facilitating metastasis as will … colorectal and gastric cancer cell migration, proliferation and …

… cells was shown to promote tumor cell growth and migration [… stimulated the migration of
breast cancer cells, and that the … cell migration, via the upregulation of RANKL expression by the …

… Both the inefficiency of current treatments of bone metastasis as well as the … In fact, the
β2-adrenergic stimulation is predominantly linked to a low bone … Increase in cell migration In vivo …

… its expression is promoted by hypoxia in cancer breast cells … and noradrenline could upregulate
the expression of VEGF … CXCR4 signaling and, thus, as inhibitor of the cellular migration […

… halt the risk of a metastasis as well as late cardiotoxicity [63]. … along with upregulating cytokines
that activate NK cells and … the adrenergic blockade so that cell migration is impeded [91]. …

… β2AR signaling in bone marrow osteoblasts increases the … MDA-231 cells to the transwell
filters (in order to block β2AR signaling specifically in cancer cells), did not inhibit cell migration …

… The same study reported a decrease in MDA-MB-231 cell migration after isoproterenol … )
expressed in osteoblasts and upregulates RANKL expression to promote osteoclastogenesis, …

… that chronic stress upregulated COX2 expression in mice and … carcinomas by enhancing
tumor cell migration and motility.… this tumor microenvironment, β2-adrenergic signaling polarizes …

… increased melanoma cells migration and invasion in vitro, and promoted lung metastasis
of … OXTRs were expressed in melanoma cells and significantly upregulated in malignant …