99mTc Auger electrons for targeted tumour therapy: A review
AAS Tavares, JMRS Tavares - International journal of radiation …, 2010 - Taylor & Francis
International journal of radiation biology, 2010•Taylor & Francis
Purpose: Targeted radiotherapy using Auger electrons presents multiple advantages and
challenges. The advantageous characteristics of this type of radiotherapy can explain the
growing interest in these specific electrons for cancer therapy. During the last decade,
Technetium-99m (99mTc) has been used as an imaging agent and only recently has it been
analysed as a potential therapeutic agent. This paper aims to be a review on the potential
use of 99mTc as a therapeutic agent. Conclusions: The physical properties of 99mTc along …
challenges. The advantageous characteristics of this type of radiotherapy can explain the
growing interest in these specific electrons for cancer therapy. During the last decade,
Technetium-99m (99mTc) has been used as an imaging agent and only recently has it been
analysed as a potential therapeutic agent. This paper aims to be a review on the potential
use of 99mTc as a therapeutic agent. Conclusions: The physical properties of 99mTc along …
Purpose: Targeted radiotherapy using Auger electrons presents multiple advantages and challenges. The advantageous characteristics of this type of radiotherapy can explain the growing interest in these specific electrons for cancer therapy. During the last decade, Technetium-99m (99mTc) has been used as an imaging agent and only recently has it been analysed as a potential therapeutic agent. This paper aims to be a review on the potential use of 99mTc as a therapeutic agent.
Conclusions: The physical properties of 99mTc along with its large availability through a generator in situ may represent a new and important pathway in targeted radiotherapy. Experimental data obtained so far has encouraged multiple researchers to investigate 99mTc further as a therapeutic agent for multiple common oncologic situations. In spite of these initial attempts to use 99mTc as a therapeutic agent beyond that of imaging, future studies are required to better define its dosimetric implications and radiobiological efficacy.
Taylor & Francis Online以上显示的是最相近的搜索结果。 查看全部搜索结果