Limited research has examined distress or help-seeking knowledge and attitudes among international students. The aim of this study was to examine psychological distress, mental health literacy (MHL), and help-seeking attitudes and intentions among a sample of domestic and international tertiary students. The sample comprised 357 domestic and international tertiary students. Participants completed an online questionnaire package, with measures relating to distress, MHL, help-seeking attitudes, and help-seeking intentions. International student status was predictive of lower scores on MHL, help-seeking attitudes, and help-seeking intentions for suicidal ideation. Student group was not predictive of help-seeking intentions for emotional problems or psychological distress, but international students had lower help-seeking intentions for suicidal ideation. Educational interventions targeting MHL and help-seeking attitudes and intentions among international students may be required to improve help-seeking behaviours.