On 2019 August 14 the Laser Interferometer Gravitational Wave Observatory (LIGO) and the Virgo gravitational wave interferometer announced the detection of a binary merger, S190814bv, with a low false alarm rate of about 1 in 1.6× 10 25 yr, a distance of 267±52 Mpc, a 90%(50%) localization region of about 23 (5) deg 2, and a probability of being a neutron star–black hole (NS–BH) merger of> 99%. The LIGO/Virgo Collaboration (LVC) defines NS–BH such that the lighter binary member has a mass of< 3 M⊙ and the more massive one has> 5 M⊙, and this classification is in principle consistent with a BH–BH merger depending on the actual upper mass cutoff for neutron stars. Additionally, the LVC designated a probability that the merger led to matter outside the final BH remnant of< 1%, suggesting that an electromagnetic (EM) counterpart is unlikely. Here we report our optical follow-up observations of S190814bv using the Magellan Baade 6.5 m telescope to target all 96 galaxies in the Galaxy List for the Advanced Detector Era catalog within the 50% localization volume (representing about 70% of the integrated luminosity within this region). No counterpart was identified to a median 3σ limiting magnitude of i= 22.2 (M i≈− 14.9 mag), comparable to the brightness of the optical counterpart of the binary neutron star merger GW170817 at the distance of S190814bv; similarly, we can rule out an on-axis jet typical of short GRBs. However, we cannot rule out other realistic models, such as a kilonova with only∼ 0.01 M⊙ of lanthanide-rich material, or an off-axis jet with a viewing angle of θ obs≳ 15.