A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

AK Manning, MF Hivert, RA Scott, JL Grimsby… - … genetics, 2012 - nature.com
… We hypothesized that genes implicated in insulin resistance pathways … accounting for
differences in body mass index (BMI) and potential interactions between BMI and genetic variants. …

On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis

RE Peterson, HH Maes, P Lin, JR Kramer… - BMC genomics, 2014 - Springer
… The meta-analyses identified 32 SNPs reaching genome-wide significance (p < 5x10 −8 ) (…
], the genome-wide load of rare CNVs was also tested by the count method. CNVs previously …

A genome-wide association study of body mass index across early life and childhood

NM Warrington, LD Howe, L Paternoster… - International journal …, 2015 - academic.oup.com
body mass index at 8 years of age and single nucleotide polymorphisms near the FAM120AOS
gene on chromosome 9 was identified… each genetic variant (ie an additive genetic model)…

An integrative framework to prioritize genes in more than 500 loci associated with body mass index

D Hemerich, V Svenstrup, VD Obrero, M Preuss… - … of Human Genetics, 2024 - cell.com
Genome-wide association studies (GWASs) have identified hundreds of genetic variants that
influence body mass index (… Most variants are non-coding and likely act through regulating …

Harnessing tissue-specific genetic variation to dissect putative causal pathways between body mass index and cardiometabolic phenotypes

GM Leyden, CY Shapland, GD Smith… - … of Human Genetics, 2022 - cell.com
… ∼900 genome-widemethod retains SNPs that have the strongest independent association
with BMI across the genome to identify the number of loci where genetic variation influences

A large multiethnic genome-wide association study of adult body mass index identifies novel loci

TJ Hoffmann, H Choquet, J Yin, Y Banda, MN Kvale… - Genetics, 2018 - academic.oup.com
variants may help prioritize causal genes, we also examined associations with gene
expression for each of the 30 genome-wide significant SNPs identified at novel BMI loci in the …

Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project

CS Fox, N Heard-Costa, LA Cupples, J Dupuis… - … medical genetics, 2007 - Springer
… , affecting roughly twelve million people and accounting for … Genetic and environmental
factors have been linked to … we identified via the GEE method is located in the SSTR2 gene, …

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

, … Genetics and Lifecourse Epidemiology … - … molecular genetics, 2016 - academic.oup.com
Genome-wide association analysis identifies three new susceptibility loci for childhood body
mass index | Human Molecular Genetics | Oxford Academic … Division of Human Genetics

Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies

M den Hoed, U Ekelund, S Brage, A Grontved… - Diabetes, 2010 - Am Diabetes Assoc
… that physical activity modifies the association of genetic variation with general adiposity in
adults (29,… Body mass and height were measured using standard procedures, with participants …

DNA methylation and body-mass index: a genome-wide analysis

KJ Dick, CP Nelson, L Tsaprouni, JK Sandling, D Aïssi… - The Lancet, 2014 - thelancet.com
… between several genetic variants and body-mass index (BMI) have been identified, little is
body-mass index and SNPs affecting methylation levels of these probes in the HIF3A locus …