… the prokaryote genome that have not been affected by horizontal gene transfer. Our prokaryotic
timeline shows deep divergences within … indicating a long evolutionary history. The early …

… methanogenesis fits well with the concept of a methanogenic root for archaea and an
autotrophic origin of … genome, and that the prokaryotic genome state that we know today (lacking …

… when we constrained the regression through the origin (P-value = … rate than other lineages
within the same timeframe. We also … Archaea: evolution of methanogenesis and methanogens …

… Abstract Background The timescale of prokaryote evolution … However, the relatively large
number of genome sequences … higher-level groupings of prokaryotes. Of particular interest is a …

… certain amino acids in prokaryotes. There are three … origin. It was further hypothesized that
the three branches of the Euryarchaeota family lost methanogenic pathways during evolution [ …

… prokaryote–eukaryote symbioses as a source of evolutionary innovation has been rapidly
increased by the advent of genomics… of symbioses during the origin and evolution of eukaryotic …

… , halophiles, methanogens, and even thermophilic methanogens. … ancient origins (without
them, interpretation of the genetic … in a recent evolutionary time scale for genetic exchanges …

… in the genomes available for this prokaryotic group. CPR bacteria have reduced genome size
… strongly suggests that nitrogenase originated first in primitive methanogenic Archaea. This …

… to (i) evaluate the evolutionary history of prokaryotes through … genomic timescale of
prokaryote evolution: insights into the … Conclusions: Our early time estimates for methanogenesis …

… By explicitly incorporating evolutionary timescale into our … LGT provides new insight into
the evolutionary history of life … Our results provide new insight into the paradox that, despite …