A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer

SY Wu, R Rupaimoole, F Shen, S Pradeep… - Nature …, 2016 - nature.com
… for regulating tumour angiogenesis. This unbiased approach led us to identify miR-192 as
a key regulator of tumour angiogenesis. In both highly angiogenic ovarian and renal cancer

Re: A miR-192-EGR1-HOXB9 Regulatory Network Controls the Angiogenic Switch in Cancer

A Atala - Journal of Urology, 2017 - journals.lww.com
… for regulating tumor angiogenesis. This approach led to the identification of miR-192 as a
key regulator of tumor angiogenesis. Highly angiogenic ovarian and renal cancer models …

MicroRNA key to angiogenesis regulation: MiRNA biology and therapy

A Tiwari, B Mukherjee, M Dixit - Current cancer drug targets, 2018 - ingentaconnect.com
… the balance in angiogenic switch, along with the angiogenic inhibitors like Angioarrestin, …
, AK A miR192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. …

HOX genes family and cancer: a novel role for homeobox B9 in the resistance to anti-angiogenic therapies

S Contarelli, V Fedele, D Melisi - Cancers, 2020 - mdpi.com
… HOX genes and their involvement in angiogenesis and cancer, with particular emphasis on
… -angiogenic therapy. HOXB9 upregulation has been reported in many types of cancers and it …

MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

P Vychytilova-Faltejskova, J Merhautova… - Oncogenesis, 2017 - nature.com
Growing evidence suggests that microRNAs are involved in the development and progression
of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-…

New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications

Y Wang, L Wang, C Chen, X Chu - Molecular cancer, 2018 - Springer
… The “angiogenic switch” is governed by pro-angiogenic and … Angiogenesis is under the
control of pro-angiogenic and anti-… of the regulatory network of miRNAs in tumor angiogenesis

lnc003875/miR-363/EGR1 regulatory network in the carcinoma-associated fibroblasts controls the angiogenesis of human placental site trophoblastic tumor (PSTT)

S Zhang, X Tao, Q Cao, X Feng, J Wu, H Yu… - Experimental Cell …, 2020 - Elsevier
controls a wide variety of pro-angiogenic genes, including Angiopoietin-1(Ang-1), VEGF, FGF2,
IL-8 and IL-6, many of which are involved in the angiogenesis … inhibit the angiogenesis of …

A study of circulating microRNAs identifies a new potential biomarker panel to distinguish aggressive prostate cancer

B Farran, G Dyson, D Craig, A Dombkowski… - …, 2018 - academic.oup.com
… comparison with healthy controls and contribute … regulation of the angiogenic switch (29)
and the cell cycle (32). Its targets comprise genes overexpressed in aggressive prostate cancer, …

miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features

Y Gu, X Wei, Y Sun, H Gao, X Zheng, LL Wong, L Jin… - Cancer research, 2019 - AACR
carcinoma (HCC), but little is known about the implications of heterogeneity and shared
molecular networks … Primary liver cancer is the second leading cause of cancer-related mortality …

microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
… the “angiogenic switch,… angiogenesis is also regulated by epigenetic states of genes, and
miRNAs expression and function (175). miRNAs act controlling the expression of angiogenesis-…