[HTML][HTML] A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1, 4-naphthoquinones
MIP Reis, VR Campos, JALC Resende… - Beilstein Journal of …, 2015 - beilstein-journals.org
Beilstein Journal of Organic Chemistry, 2015•beilstein-journals.org
… For several years, our group has been interested in developing new synthetic methods
for the preparation of heterocycle-fused 1,4-naphthoquinones or heterocycle-tethered 1,4-naphthoquinones.
1,3-Quinazolines are nitrogenated heterocycles that are present in several products.
However, there are only three … Herein we describe a new method for the synthesis of
hexahydropyrimidine-fused 1,4-naphthoquinones (13 and 21–25) in high yields, from the
sequential reaction of readily available 1,3,5-triazinanes 14–19 with 2-hydroxy-1,4-naphthoquinone …
for the preparation of heterocycle-fused 1,4-naphthoquinones or heterocycle-tethered 1,4-naphthoquinones.
1,3-Quinazolines are nitrogenated heterocycles that are present in several products.
However, there are only three … Herein we describe a new method for the synthesis of
hexahydropyrimidine-fused 1,4-naphthoquinones (13 and 21–25) in high yields, from the
sequential reaction of readily available 1,3,5-triazinanes 14–19 with 2-hydroxy-1,4-naphthoquinone …
Abstract
A new and efficient method for the synthesis of hexahydropyrimidine-fused 1, 4-naphthoquinones in one step with high yields from the reaction of lawsone with 1, 3, 5-triazinanes was developed.
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