A novel diagnostic test to screen SARS-CoV-2 variants containing E484K and N501Y mutations

Y Zhao, A Lee, K Composto… - Emerging microbes & …, 2021 - Taylor & Francis
Spike protein mutations E484K and N501Y carried by SARS-CoV-2 variants have been
associated with concerning changes of the virus, including resistance to neutralizing
antibodies and increased transmissibility. While the concerning variants are fast spreading
in various geographical areas, identification and monitoring of these variants are lagging far
behind, due in large part to the slow speed and insufficient capacity of viral sequencing. In
response to the unmet need for a fast and efficient screening tool, we developed a single …

[引用][C] A novel diagnostic test to screen SARS-CoV-2 variants containing E484K and N501Y mutations. Emerg Microbes Infect 10: 994–997

Y Zhao, A Lee, K Composto, MH Cunningham… - 2021
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