[HTML][HTML] A patient with chronic lymphocytic leukemia and acquired angioedema: correlation of clinical and biochemical response to CLL therapy
GR Mohyuddin, I Rabinowitz - ecancermedicalscience, 2013 - ncbi.nlm.nih.gov
GR Mohyuddin, I Rabinowitz
ecancermedicalscience, 2013•ncbi.nlm.nih.gov… A 65-year-old woman who was diagnosed with chronic lymphocytic leukemia (CLL), presented
with recurrent episodes of angioedema. Although no association between the CLL and
angioedema was initially recognized, further workup showed her to have low C1-INH levels.
Chemotherapy helped prevent subsequent episodes, but three years later she redeveloped …
Given the association between acquired angioedema and CLL, we decided to initiate
chemotherapy, and repeat the C1 esterase levels after completion of six cycles of rituximab …
with recurrent episodes of angioedema. Although no association between the CLL and
angioedema was initially recognized, further workup showed her to have low C1-INH levels.
Chemotherapy helped prevent subsequent episodes, but three years later she redeveloped …
Given the association between acquired angioedema and CLL, we decided to initiate
chemotherapy, and repeat the C1 esterase levels after completion of six cycles of rituximab …
Abstract
Acquired angioedema (AAE) is a result of an acquired deficiency or inactivity of the C1 esterase inhibitor (C1-INH). There is a well-known link between AAE and lymphoplasmacytic disorders.
ncbi.nlm.nih.gov
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