A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial
F Tamirou, BR Lauwerys, M Dall'Era… - Lupus science & …, 2015 - lupus.bmj.com
Background Although an early decrease in proteinuria has been correlated with good long-
term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria
value are missing, except a recent analysis performed on patients randomised in the Euro-
Lupus Nephritis Trial, demonstrating that a target value of 0.8 g/day at month 12 optimised
sensitivity and specificity for the prediction of good renal outcome. The objective of the
current work is to validate this target in another LN study, namely the MAINTAIN Nephritis …
term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria
value are missing, except a recent analysis performed on patients randomised in the Euro-
Lupus Nephritis Trial, demonstrating that a target value of 0.8 g/day at month 12 optimised
sensitivity and specificity for the prediction of good renal outcome. The objective of the
current work is to validate this target in another LN study, namely the MAINTAIN Nephritis …
[引用][C] A proteinuria cut-off level of 07g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis …
F Tamirou, BR Lauwerys, M Dall'Era, M Mackay… - DOI: https://doi. org/10.1136/lupus …
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