A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and …
A Pelaez-García, R Barderas, R Batlle… - Molecular & Cellular …, 2015 - ASBMB
Adipogenesis requires a differentiation program driven by multiple transcription factors,
where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits
adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells (mMSC). An in-
depth quantitative SILAC analysis of the nuclear fraction of Snail-induced alterations of 3T3-
L1 cells was carried out. In total, 2251 overlapping proteins were simultaneously quantified
in forward and reverse experiments. We observed 574 proteins deregulated by Snail1 using …
where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits
adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells (mMSC). An in-
depth quantitative SILAC analysis of the nuclear fraction of Snail-induced alterations of 3T3-
L1 cells was carried out. In total, 2251 overlapping proteins were simultaneously quantified
in forward and reverse experiments. We observed 574 proteins deregulated by Snail1 using …
[PDF][PDF] A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nr2f6 and IL-17 to inhibit adipocyte differentiation
A Peláez-García, R Barderas, R Batlle… - 2014 - researchgate.net
Adipogenesis requires a differentiation program driven by multiple transcription factors,
where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits
adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells (mMSC). An in-
depth quantitative SILAC analysis of the nuclear fraction of Snailinduced alterations of 3T3-
L1 cells was carried out. In total, 2251 overlapping proteins were simultaneously quantified
in forward and reverse experiments. We observed 574 proteins deregulated by Snail1 using …
where PPARγ and C/EBPα play a central role. Recent findings indicate that Snail inhibits
adipocyte differentiation in 3T3-L1 and murine mesenchymal stem cells (mMSC). An in-
depth quantitative SILAC analysis of the nuclear fraction of Snailinduced alterations of 3T3-
L1 cells was carried out. In total, 2251 overlapping proteins were simultaneously quantified
in forward and reverse experiments. We observed 574 proteins deregulated by Snail1 using …
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