A randomized placebo-controlled trial of N-acetylcysteine for cannabis use disorder in adults
KM Gray, SC Sonne, EA McClure, UE Ghitza… - Drug and alcohol …, 2017 - Elsevier
Background Cannabis use disorder (CUD) is a prevalent and impairing condition, and
established psychosocial treatments convey limited efficacy. In light of recent findings
supporting the efficacy of N-acetylcysteine (NAC) for CUD in adolescents, the objective of
this trial was to evaluate its efficacy in adults. Methods In a 12-week double-blind
randomized placebo-controlled trial, treatment-seeking adults ages 18–50 with CUD (N=
302), enrolled across six National Drug Abuse Treatment Clinical Trials Network-affiliated …
established psychosocial treatments convey limited efficacy. In light of recent findings
supporting the efficacy of N-acetylcysteine (NAC) for CUD in adolescents, the objective of
this trial was to evaluate its efficacy in adults. Methods In a 12-week double-blind
randomized placebo-controlled trial, treatment-seeking adults ages 18–50 with CUD (N=
302), enrolled across six National Drug Abuse Treatment Clinical Trials Network-affiliated …
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