system for treating solid tumors, is computationally investigated to enhance localized
delivery of drug and treatment efficacy. Integration of thermosensitive liposome (TSL), as a
doxorubicin (DOX)-loaded nanocarrier, and FUS, provides a promising drug delivery
system. A fully coupled partial differential system of equations, including the Helmholtz
equation for FUS propagation, bio-heat transfer, interstitial fluid flow, drug transport in tissue …