A strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens

JA Gold, B Rimal, A Nolan, LS Nelson - Critical care medicine, 2007 - journals.lww.com
Objective: Patients with severe alcohol withdrawal and delirium tremens are frequently
resistant to standard doses of benzodiazepines. Case reports suggest that these patients
have a high incidence of requiring intensive care and many require mechanical ventilation.
However, few data exist on treatment strategies and outcomes for these subjects in the
medical intensive care unit (ICU). Our goal was a) to describe the outcomes of patients
admitted to the medical ICU solely for treatment of severe alcohol withdrawal and b) to …

A strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens

A Hayanga, E Weiss - Critical care medicine, 2007 - journals.lww.com
We read with interest the article by Dr. Matok and colleagues (1) on the use of arginine-
vasopressin as rescue therapy in children requiring cardiopulmonary resuscitation. As in
previous studies (2–5), the authors showed that the administration of arginine-vasopressin
was effective in increasing systemic arterial blood pressure and restoring circulation.
Interestingly, these effects were seen in both children with cardiogenic shock and children
with septic shock. Usually, the administration of arginine-vasopressin is most beneficial in …
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