[HTML][HTML] A strengthening the reporting of observational studies in epidemiology (STROBE): Are HE4 and CA 125 suitable to detect a Paget disease of the vulva?
M Dellino, G Gargano, R Tinelli, C Carriero, C Minoia… - Medicine, 2021 - journals.lww.com
Paget disease is a complex disorder that can be identified in the breast (mammary Paget
disease) or in other locations (extramammary Paget's disease) such as ano-genital skin
(Paget disease of the vulva-PVD). This condition is associated with low mortality, but a late
diagnosis and recurrence can negatively impact the prognosis. Therefore, the main
objective of this study is to evaluate if the human epididymis protein 4 (HE4) and cancer
antigen125 (CA125) can promote recognition of PVD in early stages and during the …
disease) or in other locations (extramammary Paget's disease) such as ano-genital skin
(Paget disease of the vulva-PVD). This condition is associated with low mortality, but a late
diagnosis and recurrence can negatively impact the prognosis. Therefore, the main
objective of this study is to evaluate if the human epididymis protein 4 (HE4) and cancer
antigen125 (CA125) can promote recognition of PVD in early stages and during the …
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