A summary of the influence of exogenous estrogen administration across the lifespan on the GH/IGF-1 axis and implications for bone health
EA Southmayd, MJ De Souza - Growth Hormone & IGF Research, 2017 - Elsevier
Bone growth, development, and remodeling are modulated by numerous circulating
hormones. Throughout the lifespan, the extent to which each of the hormones impacts bone
differs. Understanding the independent and combined impact of these hormones on
controlling bone remodeling allows for the development of more informed decision making
regarding pharmacology, specifically the use of hormonal medication, at all ages. Endocrine
control of bone health in women is largely dictated by the growth hormone (GH)/insulin-like …
hormones. Throughout the lifespan, the extent to which each of the hormones impacts bone
differs. Understanding the independent and combined impact of these hormones on
controlling bone remodeling allows for the development of more informed decision making
regarding pharmacology, specifically the use of hormonal medication, at all ages. Endocrine
control of bone health in women is largely dictated by the growth hormone (GH)/insulin-like …
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