[HTML][HTML] A two-antibody mismatch repair protein immunohistochemistry screening approach for colorectal carcinomas, skin sebaceous tumors, and gynecologic tract …

A Mojtahed, I Schrijver, JM Ford, TA Longacre, RK Pai - Modern Pathology, 2011 - Elsevier
Mismatch repair protein immunohistochemistry is a widely used method for detecting
patients at risk for Lynch syndrome. Recent data suggest that a two-antibody panel
approach using PMS2 and MSH6 is an effective screening protocol for colorectal carcinoma,
but there are limited data concerning this approach for extraintestinal tumors. The purpose of
this study was to review the utility of a two-antibody panel approach in colorectal carcinoma
and extraintestinal tumors. We evaluated mismatch repair protein expression in two …
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